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IU trial to better target therapies for triple negative
A team at the IU Simon Cancer Center is investigating the role of genomics in improving the survival of women with triple negative breast. Byan Schneider, associate professor of medicine, and colleagues will enroll 130 women who have had chemotherapy and surgery but remain at high risk for relapse.
Half will receive the standard of care while the other half will undergo genomic sequencing. This method targets cancer cells that have remained after standard therapy and identifies mutations or changes in expression that may drive those cells. Doctors then can identify therapies to eliminate the cancer. Read more online.
Vera Bradley pledges $15 million to research
Here's another reason to buy a colorful quilted bag: The Vera Bradley Foundation for Breast Cancer has pledged $15 million to support breast cancer research at the Indiana University Melvin and Bren Simon Cancer Center. This new pledge from the Fort Wayne-based foundation adds to $20 million the company pledged previously.
The completion of this pledge will bring the total giving to the IU Simon Cancer Center to $35 million. As a result of support from the Vera Bradley Foundation for Breast Cancer, the number of IU researchers focused on breast cancer has grown to 38, up from six in 1999.
New book advises friends of cancer patient
When Cancer Strikes a Friend now is available to answer the questions and offer guidance for those who want to help their friends with cancer. A work 10 years in the making, it covers emotional and practical aspects of supporting friends.
The book is by former resident Bonnie Draeger and is a project of Friends & Cancer, a nonprofit dedicated to creating materials and learning opportunities to prepare and encourage friends to help and support people with cancer.
The book features local contibutors Gena Asher of BreastCancerFYI.org, Janice Ross of the Olcott Center for Cancer Education and Catherine Sherwood-Laughlin, IU health sciences professor who has taught a popular course on cancer. Nationally known health care professionals offer their expertise on topics from learning to communicate to finding your way as a friend. Read more about the project at the Friends & Cancer website.
Road to Recovery needs drivers
The American Cancer Society's Road to Recovery program to provide cancer patients with transportation needs some volunteers. Are you available?
The program provides drivers for cancer patients who do not have transportation to treatments or medical appointments. Volunteer drivers will be certified by spending about a half hour watching a DVD and filling out an application. The ACS will check driving records and conduct background checks.
If you are interested, contact Terri Jones at Terri.Jones@cancer.org or call (812)376-3148, or toll-free, (800)227-2345.
From the news pages:
Study looks at care for longtime survivors
People are living longer after cancer treatment than ever before, and this means the effects of their treatment may show up years later. A new study in the Journal of Cancer Survivorship found that breast cancer survivors may be at higher risk for bone density loss, high blood pressure or heart disease, depending on their treatment. Read more online.
Chemo may account for fast-track aging
Adjuvant chemotherapy for breast cancer is "gerontogenic," accelerating the pace of physiologic aging, according to a new study published in the Journal of the National Cancer Institute. These results suggest the age-promoting effects of chemotherapy last for several years after treatment, and may be permanent.
African-American women experience delays in treatment
African-American women ages 20 to 49 experience a much greater delay in treatment for breast cancer than do white women of the same ages, according to a study published in Cancer Epidemiology, Biomarkers & Prevention. Deaths from breast cancer are higher among African-American women than white women, and several studies have pointed to African-American women experiencing delays in treatment.
Obesity raises mortality in young ER+ patients
An analysis of 80,000 women with early stage breast cancer shows that obesity raises the risk of dying from the disease, according to researchers at Oxford University in England. The study found that pre-menopausal women diagnosed with estrogen receptor positive breast cancer who had a body mass index of more than 30 kg/m2 had a higher 10 year mortality rate (21.5 percent) compared with non-obese women (16.6 percent). Read more online.
More women choosing reconstruction after mastectomy
The number of women having breast reconstruction after mastectomy increased greatly from 1998 to 2007, a recent large-scale study suggests. Significant differences in the use of breast reconstruction were noted depending on geographic region, breast cancer treatment and other factors. Read more about this trend.
Drug combo may be effective against metastatic
Everolimus (Afinitor) and exemestane (Aromasin) taken at the same time may be an effective first-line treatment for hormone receptor-positive breast cancer that metastasized, or spread beyond the breast to other organs, after treatment with another aromatase inhibitor. This finding comes from a new analysis of data from the BOLERO-2 trial.
Radiation with mastectomy may benefit some
A new analysis shows that women diagnosed with early-stage breast cancer with only one to three positive lymph nodes under the arm are less likely to have a recurrence and more likely to survive breast cancer if they have radiation after mastectomy.
Breast cancer care affects debt
A study suggests that about 25 percent of long-term breast cancer survivors go into debt to pay for their treatment. Minority women are more likely to go into debt to pay for breast cancer treatment than white women. Read more about the financial consequences of fighting disease.
New ASCO guidelines say fewer may need axillary dissection
New research suggests women diagnosed with early-stage breast cancer with one or two positive sentinel nodes who have lumpectomy and radiation do just as well as women who have axillary node surgery, according to a recent study. The findings are so convincing that the American Society of Clinical Oncology has issued new guidelines on sentinel lymph node biopsy, recently published in the Journal of Clinical Oncology.
Surgery for metastatic patients may carry extra risk
Roughly 3.5 percent of all newly diagnosed breast cancer patients will present with metastatic disease, yet few have studied the postoperative complications in this group. A new study says some of the common postoperative problems that occurred often in the metastatic group included infectious, respiratory, thromboembolic, cardiac and bleeding complications.
Learn about survivors' 'Emotional Journey'
If you are a patient, survivor or caregiver, you probably have witnessed the range of emotions breast cancer patients display over the course of treatment and into survivorship. Indiana University researchers, led by Susan Woods, have released a study about just this topic, "The Emotional Journey of Long-Term Breast Cancer Survivors Five Years and Beyond," and Breast Cancer: FYI is proud to host the entire study on this website.
In the study, Woods and fellow researchers Nancy T. Ellis and Kathleen R. Gilbert look at nine themes: Changed Sense of Identity, Taking Control, Why?, Fears, Significant Milestones, Mementos, Marriage and Family, Spirituality and Words of Wisdom. One of the more powerful sections, Results, features survivors sharing their reflections on these topics. This section should be a must-read for any health professionals working with survivors, and may be useful to patients just finishing treatment, too.
Get started on the intro page, then follow the links.
More research news is available from the Archives page.